A Review on Study of Buccal Patches: Current Status of Formulation and Evaluation Methods

Amongst the various routes of drug delivery, oral route is perhaps the most preferred to the patient and the clinicians. Based on our present understandings of biochemical and physiological aspects of absorption and metabolism, many drugs cannot be delivered successfully through the conventional oral route, because after administration the drugs are subjected to extensive presystemic clearance, which often leads to a lack of significant correlation between membrane permeability, absorption and bioavailability.